Additional file 4.

Important metabolism pathways of C. sinensis. Figure S5: the glycolytic pathway of C. sinensis. All the key enzymes required for glycolysis were identified, indicating that the glycolytic pathway of C. sinensis is intact. EC numbers marked in red indicate the presence of the genes in the genome of C. sinensis. Figure S6: the Krebs cycle of C. sinensis. The Krebs cycle of C. sinensis is intact, reflected by related key enzymes present in C. sinensis genome, demonstrating that the liver fluke can generate energy from aerobic or anaerobic metabolism. EC numbers marked in red indicate the presence of the genes in the genome of C. sinensis. Figure S7: the fatty acid metabolism pathway of C. sinensis. C. sinensis can metabolize fatty acids as all required enzymes in the fatty acid metabolism pathway have been discovered. EC numbers marked in red indicate the presence of the genes in the genome of C. sinensis. Figure S8: the fatty acid biosynthesis pathway of C. sinensis. Only three enzymes in the fatty acid biosynthesis pathway were identified, indicating that C. sinensis cannot synthesize endogenous fatty acids. EC numbers marked in red indicate the presence of the genes in the genome of C. sinensis.

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Wang et al. Genome Biology 2011 12:R107   doi:10.1186/gb-2011-12-10-r107