Allele-specific copy number aberrations and ploidy in 12 colon cancer samples. Genome-wide overview of copy numbers (CN) determined by TAPS are indicated using color (see key in figure). In addition, loss of heterozygosity (LOH) is indicated using thin lines. Note the extensive presence of LOH in many samples, often coinciding with high copy numbers. Average ploidy of tumor cells calculated using TAPS and through DNA ploidy analysis.
Rasmussen et al. Genome Biology 2011 12:R108 doi:10.1186/gb-2011-12-10-r108