The ability of an organism to live in multiple habitats is the feature most correlated with the extent of codon usage bias. The 518 prokaryotes were divided into two groups - organisms who each live in a specialized environment and organisms who each live in multiple habitats - and the CAIave values of the different groups were compared. CAIave is indicated as 'Average CAI'. CAI: Codon Adaptation Index; GC: genome content.
Botzman and Margalit Genome Biology 2011 12:R109 doi:10.1186/gb-2011-12-10-r109