Correction
We have noticed an error in the sixth paragraph of the Discussion of our article [1]. The corrected paragraph should read:
Another type IV nuclease, GmrSD, found in an E. coli strain targets glucosylated hydroxymethyl-C and may have evolved to cut T4 genome [78]. The resistance of hydroxymethyl-C-containing phage to restriction enzymes but its sensitivity to McrBC [79], the resistance of glucosylated hydroxymethyl-C to McrBC but sensitivity to GmrSD [78], and inhibition of GmrSD by T4-coded internal protein [78] suggest an evolutionary arms race (evolutionary struggle between competing sets of co-evolving genes that develop adaptations and counter-adaptations against each other) between the bacteria and the phage.
References
-
Fukuda E, Kaminska KH, Bujnicki JM, Kobayashi I: Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases.
Genome Biology 2008, 9:R163. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text



