Annotation and distribution of SNPs. (a) Pfam gene families significantly (P-value < 0.01) enriched or depleted with large-effect SNPs. Asterisks indicate Pfam families statistically significantly depleted of large-effect SNPs. (b) Statistics of different types of large-effect SNPs. (c) Statistics of synonymous and non-synonymous SNPs.
Zheng et al. Genome Biology 2011 12:R114 doi:10.1186/gb-2011-12-11-r114