Genome sequence of the insect pathogenic fungus Cordyceps militaris, a valued traditional chinese medicine
- Equal contributors
1 Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
2 Chinese National Human Genome Center at Shanghai, 250 Bibo Road, Shanghai 201203, China
3 Institute of Microbiology, Chinese Academy of Sciences, 1 West Beichen Road, Beijing 100101, China
4 Department of Entomology, University of Maryland, 4112 Plant Sciences Building, College Park, Maryland 20742, USA
Genome Biology 2011, 12:R116 doi:10.1186/gb-2011-12-11-r116Published: 23 November 2011
Additional file 1:
Comparative genomics analysis of C. militaris. The file contains additional information on genomic properties and comparative gene family analysis of C. militaris with other fungi comprising 19 tables provided in separate excel sheets. Table S1 summarizes major protein family sizes of different fungal species. Table S2 provides a comparison of transposase genes among three insect pathogens. Table S3 lists the pseudogenes present in the genomes of three insect pathogens. Table S4 summarizes the protein families putatively involved in pathogen-host interactions. Table S5 compares the proteases in different fungal genomes. Table S6 lists the serine and aspartyl proteases in three insect pathogens. Table S7 lists the glycoside hydrolase families in different fungal genomes. Table S8 compares the cytochrome P450 genes in three insect pathogens. Table S9 summarizes the membrane transporters in different fungal genomes. Table S10 compares the G-protein-coupled receptors in three insect pathogens. Table S11 lists the protein kinases in three insect pathogens. Table S12 provides the information of mating- and sexuality-related genes. Table S13 lists the genes putatively involved in purine metabolisms in three insect pathogens. Table S14 summarizes the presence/absence of patulin biosynthesis homologous genes in C. militaris. Table S15 summarizes the presence/absence of T-2 toxin biosynthesis homologous genes in C. militaris. Table S16 summarizes the information from RNAseq analysis. Table S17 lists the 100 most highly expressed genes in C. militaris at different growth stages. Table S18 lists the transcriptional data of sexuality- and fruiting-related genes. Table S19 compares the expression data of genes putatively involved in signaling and transcription controls.
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Additional file 2:
Figures that provide support information for the main text. Figure S1 provides support for RIP occurring in C. militaris. Figure S2 provides support for the lack of the pentose metabolic pathway in C. militaris. Figure S3 provides a phylogeny analysis of fungal ribonucleotide reductases. Figure S4 provides the phylogeny and modular analysis of C. militaris NRPSs. Figure S5 provides a phylogeny analysis of fungal dimethylallyl tryptophan synthases. Figure S6 provides the gene transcription profiles between different samples.
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