Cordycepin analogues and the C. militaris adenine metabolic pathway. (a) The structures of cordycepin analogues. (b) The C. militaris adenine metabolic pathway. Abbreviations for different enzymes: ADA, adenosine deaminase; ADE, adenine deaminase; ADEK, adenylate kinase; ADK, adenosine kinase; ADN, adenosine nucleosidase; AMPD, AMP deaminase; APRT, adenine phosphoribosytransferase; DADK, deoxyadenylate kinase; DAK, deoxyadenosine kinase; NDK, nucleoside-diphosphate kinase; NT5E, 5'-nucleotidase; PK, pyruvate kinase; PNP, purine nucleoside phosphorylase; 3'-RNR, ribonucleotide triphosphate reductase. The red dashed lines show metabolic pathways present in other organisms but absent in C. militaris.
Zheng et al. Genome Biology 2011 12:R116 doi:10.1186/gb-2011-12-11-r116