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Highly Accessed Review

Evolution of biological interaction networks: from models to real data

Mark GF Sun1 and Philip M Kim1234*

Author Affiliations

1 Department of Computer Science, University of Toronto, 160 College St, Toronto, ON, Canada M5S 3E1

2 Department of Molecular Genetics, University of Toronto, 160 College St, Toronto, ON, Canada M5S 3E1

3 Banting and Best Department of Medical Research, 160 College St, University of Toronto, Toronto, ON, Canada M5S 3E1

4 Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, 160 College St, Toronto, ON, Canada M5S 3E1

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Genome Biology 2011, 12:235 doi:10.1186/gb-2011-12-12-235

Published: 28 December 2011

Abstract

We are beginning to uncover common mechanisms leading to the evolution of biological networks. The driving force behind these advances is the increasing availability of comparative data in several species.