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Highly Accessed Review

The domestic dog: man's best friend in the genomic era

Adam R Boyko

Author affiliations

Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305-5120, USA

Citation and License

Genome Biology 2011, 12:216  doi:10.1186/gb-2011-12-2-216

Published: 22 February 2011

Abstract

The domestic dog genome - shaped by domestication, adaptation to human-dominated environments and artificial selection - encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.