The properties and applications of single-molecule DNA sequencing
Helicos BioSciences Corporation, Building 200LL, One Kendall Square, Cambridge, MA 02139, USA
Genome Biology 2011, 12:217 doi:10.1186/gb-2011-12-2-217Published: 24 February 2011
Single-molecule sequencing enables DNA or RNA to be sequenced directly from biological samples, making it well-suited for diagnostic and clinical applications. Here we review the properties and applications of this rapidly evolving and promising technology.