Open Access Highly Accessed Research

Bringing order to protein disorder through comparative genomics and genetic interactions

Jeremy Bellay1†, Sangjo Han2,3†, Magali Michaut2,3†, TaeHyung Kim2,3, Michael Costanzo2,3, Brenda J Andrews2,3,4, Charles Boone2,3,4, Gary D Bader2,3,4,5, Chad L Myers1* and Philip M Kim2,3,4,5*

1 Department of Computer Science and Engineering, University of Minnesota, 200 Union Street SE, Minneapolis, MN 55455, USA

2 The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

3 Banting and Best Department of Medical Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

4 Department of Molecular Genetics, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

5 Department of Computer Science, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

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Genome Biology 2011, 12:R14 doi:10.1186/gb-2011-12-2-r14

Published: 16 February 2011

Additional files

Additional file 1:

Supplemental figures and tables. This text file contains Figures S1 to S25 and Table S1 with their associated legends.

Format: DOC Size: 4.1MB Download file

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Additional file 2:

Functional enrichment. This file contains three tables: a table of GO terms (function, process and component) that are enriched for flexible and constrained disorder, a table of enrichments for domains in regions of constrained disorder and a table of enrichments for domains in regions of non-conserved disorder.

Format: XLS Size: 198KB Download file

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