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Bringing order to protein disorder through comparative genomics and genetic interactions

Jeremy Bellay1, Sangjo Han23, Magali Michaut23, TaeHyung Kim23, Michael Costanzo23, Brenda J Andrews234, Charles Boone234, Gary D Bader2345, Chad L Myers1* and Philip M Kim2345*

Author Affiliations

1 Department of Computer Science and Engineering, University of Minnesota, 200 Union Street SE, Minneapolis, MN 55455, USA

2 The Donnelly Centre, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

3 Banting and Best Department of Medical Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

4 Department of Molecular Genetics, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

5 Department of Computer Science, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada

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Genome Biology 2011, 12:R14  doi:10.1186/gb-2011-12-2-r14

Published: 16 February 2011

Additional files

Additional file 1:

Supplemental figures and tables. This text file contains Figures S1 to S25 and Table S1 with their associated legends.

Format: DOC Size: 4.1MB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 2:

Functional enrichment. This file contains three tables: a table of GO terms (function, process and component) that are enriched for flexible and constrained disorder, a table of enrichments for domains in regions of constrained disorder and a table of enrichments for domains in regions of non-conserved disorder.

Format: XLS Size: 198KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data