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standard / ## Figure 4.
Performance of Hapmix and wavelet transform analysis in recovering the average number
of recombination breakpoints per Morgan of genetic distance from simulated data. The two methods were applied to 20 artificially admixed individuals, created using
a genomewide average of 20% European and 80% African ancestry. For simulated data
the average number of ancestry switches (or breakpoints) was drawn from an exponential
distribution with weight λ, such that the ancestry switch occurred with the probability
1 - e^{-λg }for each distance of g Morgans. The following values of λ were simulated: 6, 10, 20,
40, 60, 100, 200, 400. Since in the simulated genomes the true number of breakpoints
is known, we show the accuracy of both methods in recovering this information.
Pugach |