Table 1

The TRP channel familya

Drosophila melanogaster

Caenorhabditis elegansb

Ciona intestinalisb

Fugu rubripes

Danio reriob

Mus musculus

Homo sapiens


TRPC

3

3

8

8

8

7

6

TRPV

3

5

2

4

4

6

6

TRPM

1

4

2

6

6

8

8

TRPA

4

2

4

1

2

1

1

TRPN

1

1

1

-

1

-

-

TRPML

4

1

9

2

2

3

3

TRPP

1

1

1

4

4

3

3

Total

17

17

27

25

27

28

27


aTRP channels in the fruit fly Drosophila melanogaster, the worm Caenorhabditis elegans, the sea squirt Ciona intestinalis, the puffer fish (Seifuku, Fugu rubripes), the zebrafish (Danio rerio), mouse and human. The numbers correspond to proteins with distinct channel properties within each subfamily [104-106]. For more detailed information concerning properties of TRP channels, please refer to the IUPHAR database [103]. bOthers report about 60 TRPs in zebrafish, 30 in sea squirts and 24 in C. elegans.

Nilius and Owsianik Genome Biology 2011 12:218   doi:10.1186/gb-2011-12-3-218