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Highly Accessed Review

High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype

Rosangela Sozzani and Philip N Benfey*

Author Affiliations

Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina, USA

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Genome Biology 2011, 12:219  doi:10.1186/gb-2011-12-3-219

Published: 28 March 2011

Abstract

High-throughput phenotyping approaches (phenomics) are being combined with genome-wide genetic screens to identify alterations in phenotype that result from gene inactivation. Here we highlight promising technologies for 'phenome-scale' analyses in multicellular organisms.