Examples of imprinted genomic regions in fibroblasts. (a) Paternally expressed imprinted region on chr14 covering numerous non-RefSeq genes found downstream of the paternally imprinted DLK1 gene (was not informative in our samples). This region has been previously identified in mice and sheep. (b) Extension of imprinting with paternal expression downstream of the SNRPN/SNURF loci encompassing multiple non-RefSeq genes. (c) Maternally expressed imprinted gene ZNF597 with upstream imprinted isoform-specific NAT15.
Morcos et al. Genome Biology 2011 12:R25 doi:10.1186/gb-2011-12-3-r25