Table 1

Validated imprinted genes in the human genome

Location

Gene

Transcript

Human

Mouse

Expressed allele

LCL

FB

6q24

PLAGL1^a

NM_001080952

I

I

P

No

Yes

7q21

SGCE

NM_001099401

I

I

P

Yes

No

7q21

PEG10

NM_015068

I

I

P

NA

Yes

7q32

CPA4

NM_016352

I

NR

M

No

Yes

7q32

MEST

NM_177524

I

I

P

No

Yes

7q32

COPG2

NM_012133

CD

I

P

No

Yes

7q32

KLF14

NM_138693

I

I

M

NA

Yes

11p15

H19

NR_002196

I

I

M

No

Yes

11p15

KCNQ1

NM_000218

I

I

M

Yes

NA

14q32

MEG3

NR_002766

I

I

M

No

Yes

15q11

MKRN3

NM_005664

I

I

P

NA

Yes

15q11

MAGEL2

NM_019066

I

I

P

NA

Yes

15q11

NDN

NM_002487

I

I

P

NA

Yes

15q11

SNURF

NM_005678

I

I

P

Yes

Yes

15q11

IPW

NR_023915

I

I

P

Yes

Yes

16p13

ZNF597

NM_152457

I

NR

M

Yes

Yes

19q13

ZNF331

NM_001079906

I

NR

P

Yes

Yes

19q13

ZIM2

NM_015363

I

I

P

No

Yes

20q13

GNAS/GNASAS

NR_002785

I

I

M

Yes

Yes

20q13

L3MBTL

NM_032107

I

NR

P

Yes

Yes

^aOnly PLAGL1 isoform 1 is found expressed and imprinted in the fibroblasts; isoforms 1 and 2 are biallelically expressed in the LCLs. CD, conflicting evidence as defined by Morrison et al. [19]; FB, fibroblast cell lines; I, imprinted genes with previously observed parent-of-origin-dependent expression bias; LCL, lymphoblast cell lines; M, maternal; NA, not available (not expressed or non-informative in children); NR, not reported; P, paternal.

Morcos et al. Genome Biology 2011 12:R25   doi:10.1186/gb-2011-12-3-r25