Microarray accuracy rate and base calling. (a) Microarray base calling accuracy rate was calculated by comparing microarray base calls with sequence data for five parasite genomes. At more stringent discrimination scores, accuracy rate increased. SNP subsets demonstrate greater performance than average if those SNPs are more amenable to hybridization-based interrogation (NIH and Broad subsets). (b) Mean number of base calls produced at various Dscore cutoffs for all SNP loci and for SNP subsets from previously published microarray platforms (NIH and Broad).
Tan et al. Genome Biology 2011 12:R35 doi:10.1186/gb-2011-12-4-r35