Post-meiotic segregation markers are relatively isolated from other polymorphisms. Histograms showing the marker density in 100-bp windows centered on PMS markers (upper panel), centered on markers located at the end of conversion tracts (middle panel), and centered on overall markers in recombination intervals (lower panel). A range of window sizes produced qualitatively similar results. The median distance to the nearest polymorphism for markers at the end of conversion tracts was 58 bp larger than for all markers in recombination events (Wilcoxon test, P < 0.0001) and the median distance to the nearest polymorphism for PMS markers was 49 bp larger than for all end-of-interval markers (Wilcoxon test, P = 0.002).
Mancera et al. Genome Biology 2011 12:R36 doi:10.1186/gb-2011-12-4-r36