Post-meiotic segregation occurs preferentially at specific polymorphism types. (a) Relative frequencies of the possible mismatches given the SNPs found in PMS events and in recombination events (Rec. SNPs). (b) Inverse relationship between the frequency of the different SNP types in the S. cerevisiae species and the efficiency with which the mismatches generated by the SNPs are repaired (PMS relative rate = PMS frequency/Recombination SNP frequency). In the figure the frequencies of SNPs between S288c and YJM789 are shown. The result is qualitatively the same when calculating SNP frequencies with other strains .
Mancera et al. Genome Biology 2011 12:R36 doi:10.1186/gb-2011-12-4-r36