Additional file 3.Fitting the circular polymer model to mouse gene-rich loci. The circular polymer model (Equations 1 and 2b) was fitted to 3C-qPCR data obtained at gene-rich loci. The best fit curve is shown in red and best fit parameters are as follows: R2 = 0.50 with K = 725,785 ± 66,540; S = 2.515 ± 0.092 kb; c = 110.515 ± 2.028 kb. The black curve depicts the best fit obtained with the linear polymer model (Equations 1 and 2a; R2 = 0.18). Format: PDF Size: 91KB Download file This file can be viewed with: Adobe Acrobat Reader Court et al. Genome Biology 2011 12:R42 doi:10.1186/gb-2011-12-5-r42 |