Figure 2.

A schematic of the approach to the discovery of drug susceptibility-associated CNVs. We added to PACdb the CNV associations with cellular sensitivity to the chemotherapeutic agents. Note that some drug-associated CNVs (dCNVs) are poorly interrogated by SNPs and are thus independent of drug-associated SNPs (dSNPs). SCAN includes the results of eQTL mapping of CNVs to transcriptional expression.