A CNV associated with cellular sensitivity to both carboplatin and cisplatin. We identified an amplification CNV, CNVR7826_full on chromosome 20, that is associated with both carboplatin sensitivity (a) (P = 0.0056) and cisplatin sensitivity (b) (P = 0.0023). The x-axis is the copy number (3 or 4) for the CNV; the y-axis is the log2-transformed IC50.
Gamazon et al. Genome Biology 2011 12:R46 doi:10.1186/gb-2011-12-5-r46