The relationship between CCND1 expression and etoposide IC50 in the discovery set and in an independent replication set of 52 CEPH LCLs. (a) Discovery set; (b) independent replication set of 52 CEPH LCLs. Panel (b) describes the expression- IC50 relationship using real-time expression; the relationship is consistent with that in the discovery set of CEU samples.
Gamazon et al. Genome Biology 2011 12:R46 doi:10.1186/gb-2011-12-5-r46