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Refinement of primate copy number variation hotspots identifies candidate genomic regions evolving under positive selection

Omer Gokcumen12, Paul L Babb3, Rebecca C Iskow12, Qihui Zhu12, Xinghua Shi12, Ryan E Mills12, Iuliana Ionita-Laza4, Eric J Vallender25, Andrew G Clark6, Welkin E Johnson25* and Charles Lee12*

Author Affiliations

1 Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA

2 Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA

3 Department of Anthropology, University of Pennsylvania, 3260 South Street, Philadelphia, PA 19104, USA

4 Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA

5 New England Primate Research Center, One Pine Hill Drive, Southborough, MA 01772, USA

6 Department of Molecular Biology and Genetics, Cornell University, 107 Biotechnology Building, Ithaca, NY 14853, USA

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Genome Biology 2011, 12:R52  doi:10.1186/gb-2011-12-5-r52

Published: 31 May 2011

Additional files

Additional file 1:

Supporting tables. The tables of the CNVs considered in the study and summaries of additional analyses.

Format: XLS Size: 4MB Download file

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Additional file 2:

Supporting figures. Supporting figures for the manuscript.

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Additional file 3:

Supporting methods. Additional description of methodologies described in the manuscript.

Format: DOC Size: 340KB Download file

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