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Genome-wide mapping of the sixth base

Dinh Diep12 and Kun Zhang12*

Author Affiliations

1 Department of Bioengineering, University of California at San Diego, 9500 Gilman Drive, MC0412, La Jolla, CA 92093-0412, USA

2 Bioinformatics and System Biology Graduate Program, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA

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Genome Biology 2011, 12:116 doi:10.1186/gb-2011-12-6-116

Published: 20 June 2011

Abstract

Mapping of 5-hydroxylmethylcytosine in mammalian genomes has unveiled its unique role in the epigenetic regulation of gene expression.

See Research article: http://genomebiology.com/2011/12/6/R54

Keywords:
epigenetics; 5-hydroxylmethylcytosine; embryonic stem cells; Tet1