A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAs
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* Corresponding author: John L Rinn jrinn@broadinstitute.org
- † Equal contributors
Genome Biology 2011, 12:R56 doi:10.1186/gb-2011-12-6-r56
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Commentary
Noncoding RNA, antigenic variation, and the virulence genes of Plasmodium falciparum A Taylor Bright, Elizabeth A Winzeler BMC Biology 2011, 9:50 (19 July 2011) The malaria parasite P. falciparum has 60 variants of the gene encoding the major virulence factor PfEMP, variably expressed on the red blood cell surface so that it evades immune detection. Taylor Bright and Elizabeth Winzeler discuss a recent report in Genome Biology on a new family of long noncoding RNAs that may explain the selective suppression of these genes.
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