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Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study

Hiroki Goto1, Benjamin Dickins2, Enis Afgan3, Ian M Paul4, James Taylor3*, Kateryna D Makova1* and Anton Nekrutenko2*

Author Affiliations

1 The Huck Institutes of Life Sciences and Department of Biology, Penn State University, 305 Wartik Lab, University Park, PA 16802, USA

2 The Huck Institutes for the Life Sciences and Department of Biochemistry and Molecular Biology, Penn State University, Wartik 505, University Park, PA 16802, USA

3 Departments of Biology and Mathematics & Computer Science, Emory University, 1510 Clifton Road NE, Room 2006, Atlanta, GA 30322, USA

4 Department of Pediatrics, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA

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Genome Biology 2011, 12:R59  doi:10.1186/gb-2011-12-6-r59

Published: 23 June 2011

Additional files

Additional file 1:

Supplemental Figures S1, S2, S3, S4, and S5.

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Additional file 2:

Supplemental Table S1.

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Additional file 3:

FN-FP-simulation-script.py. A script for performing simulation performed in Results and discussion.

Format: PY Size: 5KB Download file

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