Figure 3.

Comparison between Rag2-/- (control) and T-bet-/- × Rag2-/- (case) mice highlighting that, at the phylum level, Firmicutes are enriched in T-bet-/- × Rag2-/- mice, whereas Actinobacteria are enriched in Rag2-/- mice. In agreement with previous culture-based studies, Bifidobacterium species are underabundant in T-bet-/- × Rag2-/- mice [68], and LEfSe highlights several additional genus-level clades, including the specifically depleted Roseburia and Papillibacter within the otherwise overabundant Firmicutes.

Segata et al. Genome Biology 2011 12:R60   doi:10.1186/gb-2011-12-6-r60
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