An integrated strategy for identification of both sharp and broad peaks from next-generation sequencing data
1 Department of Physics, The George Washington University, 725 21st Street NW, Washington DC, 20052, USA
2 Laboratory of Molecular Immunology, National Heart, Lung and Blood Institute, NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA
Genome Biology 2011, 12:120 doi:10.1186/gb-2011-12-7-120Published: 25 July 2011
A novel integrative approach has been developed by Lieb and colleagues for analyzing genome-wide datasets of different chromatin-binding factors and epigenetic states that exhibit both sharp and diffuse signals on the genome.
See research article: http://genomebiology.com/2011/12/7/r67