Research highlight
Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes
Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Genome Biology 2011, 12:121 doi:10.1186/gb-2011-12-7-121
Published: 25 July 2011Abstract
An upstream ORF cooperates with Sex lethal to inhibit msl-2 translation during Drosophila sex determination, a biological principle with potentially broad application in gene regulation.
