Table 2

Atg8 subfamilies in metazoan lineages

Number of genes

Lineage

Representative species

GATE-16

GABARAP

LC3

Mammals

Human

1

2

4

Amphibians

Xenopus tropicalis (Western clawed frog)

1

1

4

Fish

Danio rerio (zebrafish)

1

3

4

Cephalochordates

Branchiostoma floridae (amphioxus)

1

1

2

Tunicates

Ciona savignyi (Pacific transparent sea squirt)

1

1

2

Echinoderms

Strongylocentrotus purpuratus (California purple sea urchin)

2

1

2

Mollusks

Aplysia californica (California sea slug)

1

1

2

Flat worms

Schmidtea mediterranea (planarian)

Schistosoma mansoni (trematode)

1

1

1

1

1

-

Nematodes

Caenorhabditis elegans

-

1

1

Insects

Drosophila melanogaster

Apis mellifera (honey bee)

-

-

2

1

-

1

Segmented worms

Capitella teleta

1

1

2

Cnidarians

Nematostella vectensis (starlet sea anemone)

1

1

2

Sponges

Amphimedon queenslandica

2

1

2

Shpilka et al. Genome Biology 2011 12:226   doi:10.1186/gb-2011-12-7-226