Table 1

Quantitative PCR enrichment measurements from 12 clinical samples

Percentage

Parasite [DNA] (pg/μl)

Sample

parasite DNA

WGA

Pre-hybrid selectiona

Post-hybrid selectiona

Fold enrichment


Th231.08 (round 1)

0.11

Yes

1.8 (0.6)

71.1 (5.6)

39.7

Th231.08 (round 2)

7.7

No

71.1 (5.6)

349.1 (74.9)

4.9

Th145.08

20

No

198.4 (17.4)

477.6 (66.7)

2.4

Th032.09

12

No

114.7 (2.9)

372.6 (59.3)

3.2

Th029.09

3

No

33.6 (0.8)

317.3 (54.7)

9.4

Th093.09

2.8

No

28.5 (1.5)

365.6 (53.4)

12.8

Th090.08

2.3

No

37.7 (1.1)

300.4 (46.9)

8.0

Th139.08

2.1

No

23.6 (0.6)

346.2 (50.7)

14.7

Th197.08

1.1

No

14.6 (0.0)

222.7 (36.1)

15.3

Th140.08

0.99

No

9.6 (0.1)

251.5 (37.4)

26.2

Th190.08

0.64

No

5.1 (0.2)

218.7 (34.0)

43.2

Th238.08

0.53

No

6.7 (0.2)

273.4 (38.1)

41.0

Th127.09

1.6

No

26.8 (0.4)

368.5 (57.1)

13.7

Th175.08

48

Yes

275.8 (7.2)

556.9 (79.4)

2.0


aNumbers in parentheses represent standard deviations. WGA, whole genome amplification.

Melnikov et al. Genome Biology 2011 12:R73   doi:10.1186/gb-2011-12-8-r73

Open Data