Additional file 1.

Figure S1 - M+1/M isotope ratio 13C enrichment of lactate, succinate, glutamate and arachidate. (a-c) M+1/M isotope ratio 13C enrichment of (a) lactate, (b) succinate and (c) glutamate analyzed by GC-MS of the aqueous fraction from control and PPARγ agonist-treated 3T3-L1 cells incubated with 1-13C-glucose. (d) M+1/M isotope ratio 13C enrichment of arachidate analyzed by GC-MS of the organic fraction from control and PPARγ agonist-treated 3T3-L1 cells incubated with 1-13C-glucose. *P < 0.05. The metabolites have been mapped to the glycolysis, TCA cycle and fatty acid synthesis metabolic pathways. An upward pointing arrows indicates a metabolite increased in 13C enrichment by PPARγ activation, and a downward pointing arrows indicates a metabolite decreased in 13C enrichment by PPARγ activation. Parent ions were used to calculate ion ratio.

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Roberts et al. Genome Biology 2011 12:R75   doi:10.1186/gb-2011-12-8-r75