Copy number variation detection in chromosome 18 of an EBV-transformed sample. (a-d) CBS segmentation of chromosome 18 from the EBV-transformed single lymphoblastoid cell 1151 using global loess normalization (a), CGHnormaliter (b), poplowess (c), and channel clone normalization (d). The y-axis represents the log2 ratios and the x-axis represents the coordinates along the chromosome. The blue line represents the CBS segmentation line. The green region represents the duplication region called by the CGHcall program.
Cheng et al. Genome Biology 2011 12:R80 doi:10.1186/gb-2011-12-8-r80