Copy number variation detection in chromosome 21 of an EBV-transformed sample. (a-d) CBS segmentation of chromosome 21 from the EBV-transformed single lymphoblastoid cell 1160 using global loess normalization (a), CGHnormaliter (b), poplowess (c), and channel clone normalization (d). The blue line represents the CBS segmentation line. The red region represents the deletion region called by CGHcall.
Cheng et al. Genome Biology 2011 12:R80 doi:10.1186/gb-2011-12-8-r80