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This article is part of a special issue on exome sequencing.

Highly Accessed Editorial

Next-generation human genetics

Jay Shendure

Author affiliations

University of Washington, Department of Genome Sciences, Foege Building S- 250, Box 355065, 3720 15th Ave NE, Seattle, WA 98195-5065, USA

Citation and License

Genome Biology 2011, 12:408  doi:10.1186/gb-2011-12-9-408

Published: 14 September 2011

Abstract

The field of human genetics is being reshaped by exome and genome sequencing. Several lessons are evident from observing the rapid development of this area over the past 2 years, and these may be instructive with respect to what we should expect from 'next-generation human genetics' in the next few years.