Table 6

Efficacy of variant elimination due to linkage peak filtering

Family

Model

Consanguinity

Number of linkage peaks

Max LOD

Number of not synonymous exonic variants

Number of (%) not synonymous exonic variants in linkage regions


A

Recessive

First cousin offspring

15

1.2

10,982

604 (5.50)

T

Recessive

First cousins once removed offspring

5

1.51

11,353

65 (0.57)

M

Dominant

None

41

0.3

13,186

2,478 (18.79)


Smith et al. Genome Biology 2011 12:R85   doi:10.1186/gb-2011-12-9-r85

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