Table 1

Capture specificity of the three human exome capture platforms

Filtered

Mapped to genome

Uniquely mapped to genome

Uniquely mapped to TR

Uniquely mapped to TFR

Replicate^a

Reads (M)

Read length

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (MB)

NA_r1

37

PE90

3,352

85.2

2,793

81.4

2,682

53.5

1,437

63.1

2,064

NA_r2

58

PE90

5,210

79.3

4,115

76.0

3,944

56.4

2,370

67.9

3,481

NS_r1

31

PE90

2,781

86.4

2,402

82.3

2,287

54.2

1,192

67.7

1,860

NS_r2

80

PE90

7,230

85.9

6,163

82.8

5,964

55.0

3,175

67.6

4,787

AS_r1

26

PE90

2,220

84.4

1,868

74.4

1,645

58.1

1,146

60.1

1,332

AS_r2

66

PE90

5,720

78.8

4,496

69.2

3,950

54.6

2,776

56.4

3,225

^aAS, Agilent solution; NA, NimbleGen array; NS, NimbleGen solution; r1 and r2 are two replicate experiments for each platform. TFR, targeted and flanking regions; TR, targeted regions.

Asan et al. Genome Biology 2011 12:R95   doi:10.1186/gb-2011-12-9-r95