Table 1

Capture specificity of the three human exome capture platforms

Filtered

Mapped to genome

Uniquely mapped to genome

Uniquely mapped to TR

Uniquely mapped to TFR


Replicatea

Reads (M)

Read length

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (Mb)

Percent of reads

Bases (MB)

NA_r1

37

PE90

3,352

85.2

2,793

81.4

2,682

53.5

1,437

63.1

2,064

NA_r2

58

PE90

5,210

79.3

4,115

76.0

3,944

56.4

2,370

67.9

3,481

NS_r1

31

PE90

2,781

86.4

2,402

82.3

2,287

54.2

1,192

67.7

1,860

NS_r2

80

PE90

7,230

85.9

6,163

82.8

5,964

55.0

3,175

67.6

4,787

AS_r1

26

PE90

2,220

84.4

1,868

74.4

1,645

58.1

1,146

60.1

1,332

AS_r2

66

PE90

5,720

78.8

4,496

69.2

3,950

54.6

2,776

56.4

3,225


aAS, Agilent solution; NA, NimbleGen array; NS, NimbleGen solution; r1 and r2 are two replicate experiments for each platform. TFR, targeted and flanking regions; TR, targeted regions.

Asan et al. Genome Biology 2011 12:R95   doi:10.1186/gb-2011-12-9-r95

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