Table 4

Power for identifying disease-causing rare mutations

NA-r1

NA-r2

NS-r1

NS-r2

AS-r1

AS-r2


High quality genotype assigned sites

32,139

32,674

31,750

31,923

31,685

31,353

Reference genotypes

32,124

32,658

31,732

31,909

31,666

31,335

SNPs

15

16

18

14

19

18

Low quality genotype assigned sites

6,064

5,529

6,453

6,280

7,349

7,681

Uncovered

1,703

1,703

1,703

1,703

872

872


For each replicate, the 30-fold data set used for Tables 2 and 3 analyses was also used for this analysis. AS, Agilent solution; NA, NimbleGen array; NS, NimbleGen solution; r1 and r2 are two replicate experiments for each platform.

Asan et al. Genome Biology 2011 12:R95   doi:10.1186/gb-2011-12-9-r95

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