This article is part of a special issue on exome sequencing.

Open Access Highly Accessed Research

A comparative analysis of exome capture

Jennifer S Parla, Ivan Iossifov, Ian Grabill, Mona S Spector, Melissa Kramer and W Richard McCombie*

  • * Corresponding author: W Richard McCombie mccombie@cshl.edu

  • † Equal contributors

Author Affiliations

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA

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Genome Biology 2011, 12:R97  doi:10.1186/gb-2011-12-9-r97

Published: 29 September 2011

Additional files

Additional file 1:

Full bioinformatic capture analysis report. A full lane-level and sample-level report from our capture sequence data analysis pipeline. This report contains all of the statistics our standard pipeline generates. Three distinct sets of sample-level statistics are provided for the specific analyses we performed using various genomic targets of interest.

Format: XLS Size: 101KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Gene-specific coding region coverage from exome capture. A table listing all UCSC hg18 RefSeq track genes, their predicted capture coverage (percent) based on capture kit intended targets, and their actual capture coverage (percent) from our data. GeneLength depicts the combined length of the coding regions of each gene, in bases.

Format: XLSX Size: 4MB Download file

Open Data