This article is part of a special issue on exome sequencing.
Jennifer S Parla, Ivan Iossifov, Ian Grabill, Mona S Spector, Melissa Kramer and W Richard McCombie*
Corresponding author: W Richard McCombie email@example.com
Genome Biology 2011, 12:R97 doi:10.1186/gb-2011-12-9-r97
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