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Whack-an-E. coli with the morbidostat

Ofer Fridman12, Amir Goldberg13 and Nathalie Q Balaban123*

Author Affiliations

1 Racah Institute of Physics, The Hebrew University, Edmond J Safra Campus, Givat-Ram, Jerusalem 91904, Israel

2 Center for Nanoscience and Nanotechnology, The Hebrew University, Edmond J Safra Campus, Givat-Ram, Jerusalem 91904, Israel

3 Sudarsky Center for Computational Biology, The Hebrew University, Edmond J Safra Campus, Givat-Ram, Jerusalem 91904, Israel

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Genome Biology 2012, 13:140  doi:10.1186/gb-2012-13-1-140

Published: 27 January 2012

Abstract

Using a device termed the 'morbidostat', a recent study sheds new light on the determinism of genetic and phenotypic trajectories leading to high antibiotic resistance.