Prior rankings of SNPs for 100 genes where a single SNP is a clear best candidate for being the 'true' eQTN using the prior probability from the hierarchical model. The histogram shows the percentage of genes for which the putative causal site is ranked by the prior among the top 1 to 15 SNPs, 15 to 30 SNPs, and so on. Typically, the candidate region for each gene contains approximately 1,200 SNPs. The two prior models correspond to the distance model only (blue) and the distance model plus experimental annotations (red). The 100 genes analyzed here were excluded from all other analyses. BG, background.
Gaffney et al. Genome Biology 2012 13:R7 doi:10.1186/gb-2012-13-1-r7