Additional file 2.

Enzymes predicted to have similar metabolic impact to that of known drug targets. There are 29 enzymes listed for ethambutol and 2 enzymes listed for isoniazid. Each enzyme is given with its gene ID and name, the set of reactions it is essential for in the initial models (uppercase metabolite names for [13], lowercase for [14]), its function, and its category. If a reaction for which an enzyme is essential is common to both models, only one model is chosen to represent it.

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Chindelevitch et al. Genome Biology 2012 13:r6   doi:10.1186/gb-2012-13-1-r6