Research highlight
Balance of DNA methylation and demethylation in cancer development
Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA
Genome Biology 2012, 13:173 doi:10.1186/gb-2012-13-10-173
Published: 23 October 2012Abstract
Genome-wide 5-hydroxymethylome analysis of a rodent hepatocarcinogen model reveals that 5-hydroxymethylcytosine-dependent active DNA demethylation may be functionally important in the early stages of carcinogenesis.
See research article http://genomebiology.com/2012/13/10/R93 webcite
