This article is part of a special issue on epigenomics.
Balance of DNA methylation and demethylation in cancer development
Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA
Genome Biology 2012, 13:173 doi:10.1186/gb-2012-13-10-173Published: 23 October 2012
Genome-wide 5-hydroxymethylome analysis of a rodent hepatocarcinogen model reveals that 5-hydroxymethylcytosine-dependent active DNA demethylation may be functionally important in the early stages of carcinogenesis.