Figure 3.

Average methylation levels of different genomic regions of the three life stages of T. spiralis. (a, b) Average density of methylation levels (a) and percentage of methylation levels (b) (y-axis; Materials and methods) at different functional regions (x-axis). (c, d) Average density of methylation levels (c) or percentage of methylation levels (d) (y-axis) of intervals around genic regions (x-axis). Two-kilobase regions upstream and downstream of each gene were divided into 100-bp (bp) intervals. Each coding sequence or intron was divided into 20 intervals (5% per interval).