Research
Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns
1 Breakthrough Breast Cancer Research Unit and Division of Pathology, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
2 MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
3 Yale University School of Medicine, Department of Molecular Biophysics & Biochemistry and Department of Psychiatry, 266 Whitney Ave, New Haven, CT 06511, USA
4 University of St Andrews School of Medicine, Medical and Biological Sciences Building, University of St Andrews, North Haugh, St Andrews KY16 9TF, UK
5 Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
Genome Biology 2012, 13:R84 doi:10.1186/gb-2012-13-10-r84
Published: 3 October 2012Additional files
Additional file 1:
1,009 hypermethylation prone genes. Excel file containing details of the 1,009 hypermethylation prone genes in the 7 cancer types.
Format: XLS Size: 229KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
Supplementary data. PDF file containing four supplementary figures, one table and their legends.
Format: PDF Size: 1.6MB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 3:
446 variably methylated genes. Excel file containing details of the 446 variably hypermethylated genes along with their susceptibility in the different cancer types.
Format: XLS Size: 116KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 4:
220 consistently methylated genes. Excel file containing details of the 220 consistently hypermethylated genes in the 7 different types of cancer.
Format: XLS Size: 40KB Download file
This file can be viewed with: Microsoft Excel Viewer
