Figure 6.

Annotation of differentially methylated CpGs. (a) Distance to TSS for differentially methylated CpGs are plotted from ER+ versus ER- analysis. (b) Pie chart showing percentages of differentially methylated CpGs on promoters, exons, introns and intergenic regions. (c) Pie chart showing percentages of differentially methylated CpGs on CpG islands, CpG island shores (defined as 2kb flanks of CpG islands) and other regions outside of shores and CpG islands. (d) Pie chart showing percentages of differentially methylated CpGs on enhancers and other regions. ER+, estrogen receptor-alpha expressing; ER-, estrogen receptor-alpha non-expressing, TSS, transcription start site.