Research
Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions
1 Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA 99164-4236, USA
2 Department of Genetics and Genomic Sciences, Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
Genome Biology 2012, 13:R91 doi:10.1186/gb-2012-13-10-r91
Published: 3 October 2012Additional files
Additional file 1:
Figure S1 - microarray histogram quality control. (a-l) Sample histograms and box plots for microarray raw (a) and pre-processed signal values, using a RMA (Robust Multiarray Average), GC-content-adjusted algorithm for 11 male and female tissues (b-l).
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Additional file 2:
Figure S2 - cluster coefficient and connections. (a,b) Cluster coefficient versus number of connections for male (a) and female (b) network modules.
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Additional file 3:
Figure S3 - gene networks from gene modules. (a-d) Direct connection sub-networks for female and male modules: (a) female turquoise; (b) male yellow; (c) male brown; (d) male turquoise. Shape and color codes are the same as for Figure 5.
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Additional file 4:
Figure S4 - gene networks from signature lists. (a-d) Direct connection sub-networks for female and male tissue signature lists: (a) female heart; (b) female kidney; (c) male ovary; (d) uterus; (e) male heart; (f) male kidney; (g) male liver. Shape and color codes are the same as for Figure 5.
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Additional file 5:
Table S1 - differentially expressed genes in tissues.
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Additional file 6:
Table S2 - pathway enrichment in signature lists.
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Additional file 7:
Table S3 - pathway enrichment in tissue modules.
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Additional file 8:
Table S4 - epigenetic control regions and gene expression.
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Additional file 9:
Table S5 - lncRNA and epigenetic control regions.
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